Close Menu
Best in TechnologyBest in Technology
  • News
  • Phones
  • Laptops
  • Gadgets
  • Gaming
  • AI
  • Tips
  • More
    • Web Stories
    • Global
    • Press Release

Subscribe to Updates

Get the latest tech news and updates directly to your inbox.

What's On

The Best Smokeless Firepits for S’mores Without Tears

3 September 2025

Cronos: The New Dawn Review – Solid Survival Horror

3 September 2025

How Passkeys Work—and How to Use Them

3 September 2025
Facebook X (Twitter) Instagram
Just In
  • The Best Smokeless Firepits for S’mores Without Tears
  • Cronos: The New Dawn Review – Solid Survival Horror
  • How Passkeys Work—and How to Use Them
  • Review: ReMarkable Paper Pro Move
  • Dolby Atmos FlexConnect Lets You Place Speakers Anywhere
  • The Loophole Turning Stablecoins Into a Trillion-Dollar Fight
  • The Baby Died. Whose Fault Is It?
  • Paramount And Activision Strike Deal To Make Call Of Duty Movie
Facebook X (Twitter) Instagram Pinterest Vimeo
Best in TechnologyBest in Technology
  • News
  • Phones
  • Laptops
  • Gadgets
  • Gaming
  • AI
  • Tips
  • More
    • Web Stories
    • Global
    • Press Release
Subscribe
Best in TechnologyBest in Technology
Home » In a World First, a Patient’s Antibody Cells Were Just Genetically Engineered
News

In a World First, a Patient’s Antibody Cells Were Just Genetically Engineered

News RoomBy News Room15 December 20233 Mins Read
Share Facebook Twitter Pinterest LinkedIn Tumblr Reddit Telegram Email
Share
Facebook Twitter LinkedIn Pinterest Email

Our B cells help prevent us from getting sick. Their job is to make antibodies, immune system proteins that fight off viruses and other foreign invaders. And they make a lot of antibodies—thousands of them every second. What if these antibody factories could be harnessed to make other things the body needs?

That’s the idea behind a trial launched by Seattle-based biotech company Immusoft. The company announced today that its scientists have genetically programmed a patient’s B cells and put them back in his body in an effort to treat disease. It’s the first time engineered B cells have been tested in a person.

The patient has a genetic disorder known as mucopolysaccharidosis type I, or MPS I. His body doesn’t produce an essential enzyme that helps to break down long-chain sugars inside cells. Without this enzyme, these sugars build up in the eyes, heart, bones, and elsewhere.

The effects are life-threatening. Patients have cloudy eyes, respiratory problems, cognitive issues, and enlarged organs. Those with the most severe form of the disease die in childhood. Others may live to their twenties or thirties.

Patients are currently treated with weekly infusions of the enzyme their body lacks. The therapy must be given for the entirety of a patient’s life. Typically, a gene called IDUA provides instructions for making this enzyme, but people with MPS I have a mutation in this gene. Immusoft’s aim is to override this problem by prompting a person’s B cells to make the enzyme instead. B cells appealed to Immusoft because of their ability to pump out lots of proteins. If a person’s B cells could provide a continuous supply of this enzyme, it could eliminate the need for regular infusions.

Sean Ainsworth, CEO of Immusoft, says the initial patient is doing well after receiving the experimental therapy in mid-November. “So far, so good,” he says.

Researchers at the company collected the patient’s B cells using a machine that removes blood, separates out a particular component, then returns the rest to circulation. There are billions of B cells in the body; Immusoft uses only a portion. “The body is constantly regenerating and producing new B cells,” Ainsworth says.

To get the B cells to produce the missing enzyme in addition to antibodies, scientists had to add new genetic instructions to them in the lab. They packaged those instructions into a transposon, a DNA sequence that can naturally integrate into a cell’s genome using a cut-and-paste mechanism.

Share. Facebook Twitter Pinterest LinkedIn Tumblr Email
Previous ArticleVivo S18 Pro, Vivo S18 and Vivo S18e With AMOLED Screens, 50-Megapixel Cameras Launched: Price, Specifications
Next Article How Digital Eclipse redefined the remaster in 2023 with The Making of Karateka

Related Articles

News

The Best Smokeless Firepits for S’mores Without Tears

3 September 2025
News

How Passkeys Work—and How to Use Them

3 September 2025
News

Review: ReMarkable Paper Pro Move

3 September 2025
News

Dolby Atmos FlexConnect Lets You Place Speakers Anywhere

3 September 2025
News

The Loophole Turning Stablecoins Into a Trillion-Dollar Fight

3 September 2025
News

The Baby Died. Whose Fault Is It?

3 September 2025
Demo
Top Articles

ChatGPT o1 vs. o1-mini vs. 4o: Which should you use?

15 December 2024105 Views

Costco partners with Electric Era to bring back EV charging in the U.S.

28 October 202495 Views

5 laptops to buy instead of the M4 MacBook Pro

17 November 202491 Views

Subscribe to Updates

Get the latest tech news and updates directly to your inbox.

Latest News
News

The Loophole Turning Stablecoins Into a Trillion-Dollar Fight

News Room3 September 2025
News

The Baby Died. Whose Fault Is It?

News Room3 September 2025
Gaming

Paramount And Activision Strike Deal To Make Call Of Duty Movie

News Room3 September 2025
Most Popular

The Spectacular Burnout of a Solar Panel Salesman

13 January 2025129 Views

ChatGPT o1 vs. o1-mini vs. 4o: Which should you use?

15 December 2024105 Views

Costco partners with Electric Era to bring back EV charging in the U.S.

28 October 202495 Views
Our Picks

Review: ReMarkable Paper Pro Move

3 September 2025

Dolby Atmos FlexConnect Lets You Place Speakers Anywhere

3 September 2025

The Loophole Turning Stablecoins Into a Trillion-Dollar Fight

3 September 2025

Subscribe to Updates

Get the latest tech news and updates directly to your inbox.

Facebook X (Twitter) Instagram Pinterest
  • Privacy Policy
  • Terms of use
  • Advertise
  • Contact Us
© 2025 Best in Technology. All Rights Reserved.

Type above and press Enter to search. Press Esc to cancel.